Discriminant models of the possibility of genital endometriosis in Ukrainian young women depending on the features of the structure and body size

Abstract

Endometriosis is one of the most common gynecological pathologies, which can significantly affect the reproductive health of women, including young women. Research into factors that may contribute to its development is important for early identification of risk groups and development of preventive measures. Among the possible predictors, anthropometric characteristics that may reflect the endocrine and metabolic characteristics of the body attract attention. The study of these parameters allows us to assess the potential relationship between somatotype and the likelihood of developing the disease, which may contribute to a personalized approach to prevention. The aim of the study is to construct and analyze discriminant models of the possibility of genital endometriosis in Ukrainian young women without and with somatotype, depending on the features of the structure and body size. Clinical, laboratory and anthropo-somatotypological examination were performed on 89 Ukrainian young women (aged 16 to 18 years) with genital endometriosis. Primary anthropo-somatotypological indicators of 78 practically healthy Ukrainian young women of the same age group were taken from the data bank of the National Pirogov Memorial Medical University, Vinnytsya, Ukraine. Discriminant models of the possibility of the occurrence and features of the course of genital endometriosis, depending on the features of the structure and body size, were constructed in the “Statistica 6.0” license package. It was established that when dividing Ukrainian young women into practically healthy and patients with genital endometriosis both without taking into account the somatotype and in representatives of mesomorphic, ectomorphic and ecto-mesomorphic somatotypes, reliable (p<0.001 in all cases) highly informative (correctness of entry into the models of anthropo-somatotypological indicators is from 98.6 % to 100 % of cases; Wilks’ Lambda statistics is from 0.084 to 0.039) discriminant models of the possibility of the occurrence of this disease depending on the features of the body structure and body dimensions. The most common components of the constructed models include: in the group without taking into account the somatotype - girth dimensions of the body and trunk diameters of 33.33 % each; in mesomorphs - girth dimensions of the body 42.86 % and trunk diameters 28.57 %; in ectomorphs – girth dimensions of the body 50.00 %, trunk diameters and width of the distal epiphyses of the long tubular bones of the limbs 25.00 % each; in ecto-mesomorphs – girth dimensions of the body in 100 % of cases.