Abstract:
Despite a fairly large amount of literature data about the involvement of hydrogen
sulfide in physiological and pathophysiological processes, its role in gastrointestinal tract
functioning has not been studied sufficiently. This review systematizes and generalizes
the mechanisms of H2
S-associated regulation of gastrointestinal secretion and motility
on the basis of literature sources processing and own research results. We analysed
world professional literature and sources in Google Scholar, PubMed, MedLine, Embase,
Cochrane, and data from more than 50 articles and books on the problem were processed
in the article. This review gives a synopsis of the H2
S function in the regulation of the
secretory and motor-evacuation function, and in stimulating the reparative properties of
the digestive tract, and indicates the main mechanisms
