Peculiarities of synoviocytes and chondrocytes proliferative activity in rats with experimental model of undifferentiated dysplasia of connective tissue

Abstract

The purpose of the work was to study the dynamics of proliferative activity of the synovial membrane cells of the jointcapsule and articular cartilage chondrocytes of rats in the postnatal period on the background of experimental model of undifferentiated dysplasia of connective tissue. It was formed in Wistar rats by means of subcutaneous injection with humanimmunoglobulin on the 18th day of fetal period of development according to the method elaborated by N. A.Voloshyn (1981). It was revealed, that during the first two weeks after birth in experimental rats proliferative activity of synovial membrane cells is significantly decreased in comparison with control.