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dc.contributor.author Storozhenko, K. V. en
dc.contributor.author Shkarupa, V. M. en
dc.date.accessioned 2018-10-08T16:13:13Z
dc.date.available 2018-10-08T16:13:13Z
dc.date.issued 2017
dc.identifier.citation Storozhenko K. V. Association of FGFR2 (rs2981579) Gene Polymorphism with the Risk of Mesial Occlusion / K. V. Storozhenko, V. M. Shkarupa // Cytology and genetics. - 2017. - Vol. 51, No. 5. - P. 361-364. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/3079
dc.description.abstract The molecular-genetic testing of the polymorphic rs2981579 (C>T) locus of the FGFR2 gene as the marker of increased predisposition to the development of mesial occlusion was carried out in 110 patients with mesial occlusion and 103 general-population control subjects from Ukraine. It was shown that polymorphism rs2981579 in gene FGFR2 is associated with mesial occlusion (OR = 1.67, 95% CI = 1.14–2.45, p = 0.009). Compared to CC carriers, TT+CT carriers had a 3.21-fold higher risk of mesial occlusion (95% CI = 1.57–6.57, p = 0.001). We found the protective effect of the homozygous allele C on mesial occlusion development (OR = 0.31, p = 0.001). This is the first published data on FGFR2 polymorphisms rs2981579 (C>T) in patients with mesial occlusion. en
dc.language.iso en en
dc.subject mesial occlusion en
dc.subject gene polymorfism en
dc.subject FGFR2 en
dc.title Association of FGFR2 (rs2981579) gene polymorphism with the risk of mesial occlusion en
dc.type Article en


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