Effect of bougienage and washing of the pancreatic duct on the course of experimental acute pancreatitis

Abstract

The presence of many hypotheses of the development of acute pancreatitis such as pancreatic duct hypertension, pancreatic ref tux, vascular, allergic, neuro-reflex, infectious, etc. confirm the lack of a dear understanding of the development mechanisms of this pathology, and hence inaccuracy in the treatment and negative consequences. The purpose of this study was to investigate the effect of bouginage and flushing of the pancreatic duct on the course of experimental acute pancreatitis. Experiments were carried out on 12 dogs, for which amodel of pancreatitis was created byautobile administration into the pancreas duct. Animals were divided into four groups, 3 animals per each, with the term ofdeduce from the test in one, three, seven days and six months respectively.