Abstract:
Alcohol is perhaps the oldest of all known psycho-active substances, which is widely used by the population of the globe in large quantities. Treatment of acute poisoning in all countries is carried out according to standardized protocols of medical care, which, depending on the stage and severity of intoxication, include drugs of different pharmacological groups: plasma substitutes, tranquilizers, opiate receptor antagonists, drugs that accelerate alcohol metabolism and its metabolism, enterosorbents. The global nature of the problem of treatment of alcohol poisoning, pharmacological properties (including sorption and prebiotic), virtually no toxicity and side effects, the ability to form a gel-like protective layer between the contents and mucous membranes of the gastrointestinal tract and the potential of domestic production of apple pectin. The aim of the research was ˗ experimental study of the effect of pectin on the histrostructure of the liver in acute and chronic alcohol intoxication. Morphological researches of liver tissue in acute and subchronic alcohol intoxication confirm the detoxifying and organoprotective effect of apple pectin, as its use in the treatment regimen reduces the intensity of dystrophic changes and regression of fatty liver, restores reparative changes in polycystic ovary disease.
