Characteristics of endothelial dysfunction in patients with atopic dermatitis

Abstract

Skin lesions in atopic dermatitis (AD) are apparently associated with vascular changes, as blood vessels provide pathways for the transport of immune cells. The aim of the study: study of the state of endothelial dysfunction in patients with atopic dermatitis.Materials and methods. 70 patients with AD were examined. Groups were formed depending on the SсORAD index (I subgroup – with SсORAD index up to 20 points, II – with SсORAD index 20-40 points, III subgroup – with SсORAD index from 40 and above points). Indicators of endothelial dysfunction of VEGF and VCAM-1 in blood serum were determined by the immunoenzymatic method.