Evaluation of gene polymorphism of IL-1β and IL-10 in children with nephrotic syndrome

Abstract

Estimating the prevalence of chronic kidney disease (CKD) in children and investigating markers of the prognosis and progression are the priority for public health. Approximately 9 in every 1 million children in the developed world require renal replacement therapy treating end-stage renal disease of CKD. The prevalence of CKD and end-stage renal disease is growing worldwide. Taking into account the considerable prevalence and progression of CKD in children, findings effective methods of the prevention of this disease is important goal of all pediatric nephrologists. The issue of early onset of prophylaxis, the individual factors of progression of CKD not completely understood.