Cobalamin (Vitamin B12) status in patients with antiphospholipid syndrome (APS), its association with atherosclerotic vascular lesions

Abstract

To evaluate vitamin B12 status in patients with antiphospholipid syndrome (APS) and to explore its relationship with atherosclerotic vascular lesion 82 patients with APS and 37 healthy individuals were observed. Content of cobalamin (vitamin B12) in serum were determined by immunochemical detection (ECLIA). It was founded that in patients with APS low cobalamin status is associated with subclinical manifestations of atherosclerotic vascular lesions.