The influence of the additional usage of l-arginine on the factors of vasodilation and the clinical data, complicated with cardiac decompensation with reduced and preserved fracture of the left ventricle that patients with stable coronary heart disease have

Abstract

Introduction: The endothelial dysfunction is one of the most difficult forms of vascular malformation. The dominant ferment, that provides the synthesis NO in the blood-making stream, is the endothelial NO-synthase, that is produced on the endothelium and plays an important role in the basic level NO support (Erdei et al., 2014; Cwynar et al., 2015). It is proved that the reduction of the activity еNOS leads to the decrement NO production and is one of the key elements of pathogenesis coronary heart disease (CHD) (Zaremba, 2012). The aim of the research: to estimate the influence of the additional usage of L-arginine hydrochloride on the factors of vasodilation and the clinical data, complicated with cardiac decompensation with impaired and reserved ejection fraction of the left ventricle that patients with stable CHD have.