Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy

Konkov, D.

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Кафедра акушерства і гінекології №1
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Наукові публікації каф. акушерства і гінекології №1
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dc.contributor.author	Konkov, D.	en
dc.date.accessioned	2017-10-18T15:37:15Z
dc.date.available	2017-10-18T15:37:15Z
dc.date.issued	2017
dc.identifier.citation	Konkov D. G. Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy / D. G. Konkov // Вісник Вінницького нацІонального медичного університету. - 2017. - Т.21, №1, ч. 2. - С. 213-216.	en
dc.identifier.uri	https://dspace.vnmu.edu.ua/123456789/1097
dc.description.abstract	The fibrinolytic imbalance might have a pivotal role in hypercoagulability seen in gestational endotheliopathy. Our objective was to determine the novel fibrinolytic markers of blood coagulation related factors in placental tissue in preeclamptic and normal pregnancies. 61 specimens of the placental tissues were obtained after delivery at physiological pregnancy, gestational endotheliopathy and preeclampsia. There were investigated placental expressions of plasminogen activator inhibitor-1 (PAI-1) and tissue- type plasminogen activators (t-PA). It was found that preeclampsia was accompanied by the significant decrease of the placental expression of t-PA and increase placental levels of PAI-1.	en
dc.language.iso	en	en
dc.publisher	ВНМУ ім. М. І. Пирогова	uk
dc.subject	gestational endotheliopathy	en
dc.subject	preeclampsia	en
dc.subject	placenta	en
dc.subject	t-PA
dc.subject	PAI-1
dc.title	Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy	en
dc.type	Article	en