Короткий опис (реферат):
Human skin is the first barrier to protect the body from external factors. Combinations
of certain external and internal (genetically determined) factors can lead to cancer of
this organ. One of such pathologies is nevi - still little studied disease. At the same
time, modern medicine is interested in inventing mechanisms to predict their occurrence
and course. The purpose of the study is to build and analyze discriminant models of the
possibility of benign nevi in Ukrainian men depending on the characteristics of
dermatoscopic parameters. Ukrainian men aged 22 to 35 years, patients with melanocyte
benign simple nevi (n=34), melanocyte benign dysplastic nevi (n=27), melanocyte
benign congenital nevi (n=14) and non-melanocyte benign nevi (n=17) get dermatoscopic
examination. The possibility of benign nevi occurrence depending on the characteristics
of dermatoscopic parameters was carried out using discriminant analysis in the licensed
statistical package "Statistica 5.5". With the help of discriminant analysis, reliable
models of the possibility of occurrence of benign nevi depending on the characteristics
of dermatoscopic parameters are built. It was found that among patients with melanocyte
benign simple, dysplastic, congenital and non-melanocyte benign nevi, a reliable
interpretation of the obtained classification indicators is possible (discriminant function
covers 70.7 % of cases; statistics Wilks' Lambda=0.185; p<0.001). The models include
the general dermatoscopic index, the dermatoscopic criterion "Asymmetry" according
to the ABCD system, the number of nevi on the body more than 1 cm and the
dermatoscopic criterion "Color" according to the ABCD system. Moreover, the general
dermatoscopic index and the dermatoscopic criterion "Asymmetry" according to the
ABCD system make the greatest contribution to discrimination between Ukrainian men
with benign nevi.
Keywords: skin diseases, benign nevi, dermatoscopy, men, discriminant analysis.
