Macroscopic and microscopic conditions of the single kidney and ureteropelvic junction after the contralateral nephrectomy

Abstract

To date, there is no single concept on the patterns of morphogenesis of a single kidney compensatory hypertrophy. The purpose of the work is to give macroscopic and microscopic characteristics of the single kidney and the ureteropelvic junction structure after nephrectomy in the experiment. The experimental study was performed on 84 sexually matured white male rats weighing 180-200 g. All animals of the experimental group underwent surgery: nephrectomy of the left kidney. Statistical processing of the obtained results was carried out by means of the “Statistica 5.5” license package using non-parametric methods of assessing the results. It is established that in a single kidney there are processes of gradual developing compensatory hypertrophy of the organ. The sequential periods of postoperative changes were identified.