Короткий опис (реферат):
Malignant transformation of benign nevi is one of the factors that leads to increased
scientific interest in the study of the pathogenesis of their occurrence, the influence of
external factors on them, etc. One of the still unsolved issues is the study of the
relationship between the features of nevi indicators and the anthropometric parameters
of the human body. The purpose of the work is to investigate the peculiarities of
correlations of the dermatoscopic index with anthropometric and somatotypological
indicators of Ukrainian men with benign nevi. A clinical, laboratory and pathogistological
examination of 34 Ukrainian men of first adulthood with melanocytic benign simple
nevi, 27 with melanocytic benign dysplastic nevi, 14 with melanocytic benign congenital
nevi, and 17 with non-melanocytic benign nevi was carried out. The dermatoscopic
index was calculated according to the "ABCD rule of dermatoscopy". Anthropometric
examination was carried out according to Bunak's scheme. The Heath-Carter
mathematical scheme was used to assess the somatotype. Matiegka formulas were
used to calculate fat, bone and muscle components of body mass. In addition, the
muscle component of body weight was estimated according to the method of the
American Institute of Nutrition. The assessment of correlations between the
dermatoscopic index and body parameters was carried out in the license package
"Statistica 6.0" using the non-parametric method of Spearman. An analysis of multiple
reliable and average strength of unreliable correlations between the value of the
dermatoscopic index and anthropo-somatotypological indicators in men with benign
nevi was performed. In men with simple melanocytic nevi, only moderately strong direct
(r = from 0.30 to 0.34), mostly unreliable, correlations with all sizes of the pelvis were
established. In men with melanocytic dysplastic nevi, inverse correlations of medium
strength, mostly reliable (r = from -0.38 to -0.52) were established with all dimensions
of the pelvis and almost all transverse dimensions of the trunk, as well as with almost
half of the indicators of the skinfold thickness. In men with melanocytic congenital nevi,
direct, mostly unreliable (r = from 0.30 to 0.47) correlations were established with all
dimensions of the pelvis, with almost all transverse dimensions of the trunk, with
almost half of the girth of the body and indicators of the skinfold thickness and almost
all indicators of the component composition of body weight. In men with non-melanocytic
nevi, direct, mostly unreliable (r = from 0.30 to 0.47) correlations were established with
all transverse dimensions of the trunk and pelvis, most of the total and girth dimensions
of the body. Quantitative analysis of reliable and average strength of unreliable
correlations between the value of the dermatoscopic index and anthroposomatotypological indicators was also carried out. The established features of the correlations expand modern ideas about the risk of benign nevi.
