Peculiarities of clinical, anamnestic and dermatological indicators in Ukrainian men and women with urticaria

Abstract

The basis of optimal prevention of urticaria in most cases is to establish the exact causes of this disease, which is far from an easy task. In fact, the elimination of the suspected stimulating stimulus allows to achieve remission, in which the patient's condition normalizes for a fairly long period of time and the patient's quality of life improves significantly. The purpose of the work is to establish the peculiarities of clinical, anamnestic and dermatological indicators in patients with acute and chronic urticaria of a mild and severe course in young Ukrainian men and women. A clinical, anamnestic and dermatological examination of 40 Ukrainian men and 40 young Ukrainian women with acute and chronic urticaria of mild and severe course was carried out. Urticaria was diagnosed according to the EAACI/GA²LEN/EuroGuiDerm/APAAACI international guidelines. All patients underwent a questionnaire to determine the nature of work and various negative factors affecting the skin, as well as to determine the dermatological status. To assess the degree of negative impact of urticaria on various aspects of the patient's life, a dermatological quality of life index was determined. Statistical processing of the research results was carried out with the help of the license package "Statistica 6.0" using non-parametric methods of evaluating the obtained results. As a result of the conducted research, it was established that regardless of the form of urticaria in men with a severe course of the disease, the frequency of representatives with the physical nature of work, the presence of an allergic reaction, the presence of a stress factor in the anamnesis, the presence of pain in the affected area of the skin, on the mucous membrane, on the limbs is increasing, the presence of angioedema of the skin and higher values of the dermatological index; and in women with a severe course of the disease – the presence of an allergic reaction, the factor of taking drugs, the presence of pain in the area of skin damage, on the scalp and mucous membrane, angioedema of the skin and higher values of the dermatological index. In men with a mild course of the disease, the frequency of representatives with the mental nature of work and the presence of the moisture factor increases; and in women with a mild course of the disease – the insolation factor. Among patients with the acute form of urticaria, men with a mental nature of work and women with the presence of the humidity factor, a burning sensation in the affected area of the skin and on the limbs predominate; and among patients with a chronic form of urticaria – men with an allergic reaction, with the presence of a seasonality factor, with localization of skin lesions on the scalp and skin on the face, and women with a mixed nature of work, a seasonality factor, insolation.