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Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy

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dc.contributor.author Konkov, D. G. en
dc.date.accessioned 2017-07-05T13:55:53Z
dc.date.available 2017-07-05T13:55:53Z
dc.date.issued 2017
dc.identifier.citation Konkov D. G. Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy / D. G. Konkov // Вісник Вінницького нацІонального медичного університету. - 2017. - Т. 21, № 1, ч. 2. - С. 213-216. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/736
dc.description.abstract The fibrinolytic imbalance might have a pivotal role in hypercoagulability seen in gestational endotheliopathy. Our objective was to determine the novel fibrinolytic markers of blood coagulation related factors in placental tissue in preeclamptic and normal pregnancies. 61 specimens of the placental tissues were obtained after delivery at physiological pregnancy, gestational endotheliopathy and preeclampsia. There were investigated placental expressions of plasminogen activator inhibitor-1 (PAI-1) and tissue- type plasminogen activators (t-PA). It was found that preeclampsia was accompanied by the significant decrease of the placental expression of t-PA and increase placental levels of PAI-1. en
dc.language.iso en en
dc.publisher Вісник Вінницького нацІонального медичного університету uk
dc.subject gestational endotheliopathy en
dc.subject preeclampsia en
dc.subject placenta en
dc.subject PAI-1
dc.subject t-PA
dc.title Placental expression of plasminogen activator inhibitor-1 and tissue- type plasminogen activators in gestational endotheliopathy en
dc.title.alternative Плацентарна експресія інгібітора активатора плазміногену (РАІ-1) та тканинного активатора плазміногену (t-PA) при гестаційній ендотеліопатії uk
dc.title.alternative Плацентарная экспрессия ингибитора активатора плазминогена (РАІ-1) и тканевого активатора плазминогена (t-PA) при гестационной эндотелиопатии ru
dc.type Article en


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