Impact of line probe assay-based molecular testing on individualized treatment in patients with rifampicin-resistant tuberculosis: data from the prospective INNOVA4TB cohort study in Ukraine

Dudnyk, A.; Hempel, M.; Lytvyniuk, O.; Liudkevych, H.; Matsera, V.; Nikitchenko, T.; Blyzniuk, S.; Molina-Moya, B.; Preyer, R.; Domínguez, J.

dc.contributor.author	Dudnyk, A.	en
dc.contributor.author	Hempel, M.	en
dc.contributor.author	Lytvyniuk, O.	en
dc.contributor.author	Liudkevych, H.	en
dc.contributor.author	Matsera, V.	en
dc.contributor.author	Nikitchenko, T.	en
dc.contributor.author	Blyzniuk, S.	en
dc.contributor.author	Molina-Moya, B.	en
dc.contributor.author	Preyer, R.	en
dc.contributor.author	Domínguez, J.	en
dc.date.accessioned	2025-03-08T11:33:41Z
dc.date.available	2025-03-08T11:33:41Z
dc.date.issued	2024
dc.identifier.citation	Impact of line probe assay-based molecular testing on individualized treatment in patients with rifampicin-resistant tuberculosis: data from the prospective INNOVA4TB cohort study in Ukraine / A. Dudnyk, M. Hempel, O. Lytvyniuk [et al.] // Therapeutic Advances in Respiratory Disease. – 2024. – Vol. 18. – P. 1–18.	en
dc.identifier.other	DOI: 10.1177/17534666241249841	en
dc.identifier.uri	https://dspace.vnmu.edu.ua/123456789/7130	en
dc.description.abstract	Ukraine remains a high World Health Organization priority country for drug-resistant tuberculosis (TB). Rifampicin-resistant TB (RR-TB) has a more protracted, more complicated, and more expensive treatment. In 2021, Ukraine reported 4025 RR-TB cases – 5.4 times more (751) than all 30 European Union/ European Economic Area countries together. The objective of the study was to determine the diagnostic accuracy of line probe assay (LPA), AID Autoimmun Diagnostika GmbH, for detecting resistance to anti-TB drugs and its clinical application for selecting treatment regimens.	en
dc.language.iso	en	en
dc.publisher	Therapeutic Advances in Respiratory Disease	en
dc.subject	drug-resistant tuberculosis	en
dc.subject	line probe assay	en
dc.subject	molecular diagnostics	en
dc.subject	TB treatment	en
dc.title	Impact of line probe assay-based molecular testing on individualized treatment in patients with rifampicin-resistant tuberculosis: data from the prospective INNOVA4TB cohort study in Ukraine	en
dc.type	Article	en