Analysis of the range of plant-based medicines for local application in dentistry

Abstract

Actuality. Diseases of the oral mucosa are found in almost all people. At first glance, non-serious diseases can later cause complications for other vital organs. Evaluating local changes and general manifestations of the disease, treatment should be comprehensive. Currently, more and more attention is paid to local agents that have a direct effect on the pathogen and eliminate changes caused by the course of the inflammatory process. Therefore, the study of the pharmaceutical market of phytopreparations for local use in dentistry is relevant. The aim of research was to analyze the range of plant-based medicines for local use in dentistry on the pharmaceutical market of Ukraine. Materials and methodsof research. The study of the assortment of drugs was carried out according to the directory of medicines Compendium online, the State Register of Medicines of Ukraine, Anatomical Therapeutic Chemical classification (group of medicines code A01 – remedies for use in dentistry), online resources for the search of drugs in pharmacies of Ukraine – Tabletki.ua and Apteki.ua. The following methods are used: mathematical and statistical, graphic, marketing and logical generalization. The obtained data are systematized and presented in diagrams with explanations and corresponding conclusions. Research results and their discussion. As of the end of 2023, there are 33 trade names of medicinal products for local use in dentistry in Ukraine. In the pharmaceutical market of Ukraine, domestic drugs dominate, accounting for 79%. Among the domestic manufacturing companies, the first place in the nomenclature of drugs belongs to Ternopharm LLC (23%). It was established that domestic pharmaceutical companies supply medicinal plant raw materials, tinctures, drops, liquids, extracts, and gels to the pharmaceutical market of Ukraine. Also, drugs for local use in dentistry are supplied to the domestic market by manufacturing companies from countries such as Germany (57%), Poland (29%), and France (14%). The drugs we analyzed are available in various dosage forms, including medicinal plant raw material (46%), solution (18%), tincture (12%), gel (9%), tablets (6%), drops (1%), liquid (1%), and extract (1%). Among the registered medicines for local use in dentistry, 58% of the assortment is made up of monopreparations, 36% – combined medicines, the share of two-component drugs is insignificant and amounts to 6%. Conclusion. A study of the domestic market of herbal medicines for local use in dentistry was conducted, and the structure of this market segment was determined. Among Ukrainian manufacturers, the market of plant-based medicines is primarily represented by medicinal plant raw materials. However, among foreign manufacturers, it consists mainly of solutions, tablets, and gels characterized by ease of use, dosage stability, longer shelf life, and other qualities that make them attractive to many patients. Therefore, the development of such domestic medicinal forms based on plant raw materials remains relevant.