Assessment of the influence of uterine appendages torsion on their pathomorphological changes in the experiment

Abstract

The aim: The study of pathomorphological changes in uterine appendages during torsion of different duration and after their detorsion in the experiment on rats. Materials and methods: Experimental studies were performed on the basis of vivarium in the conditions of chronic experiment on 48 females of outbred white rats weighing 200.0 ± 20.0 grams.The essence of the experimental model is that the female rats, under the ketamine’s anesthesia at the rate of 1-2 mg / kg of the drug, conduct a right-sided ovary twist at 7200 in the projection of the oviduct with fixation of the organs with an external clip of indifferent metal. Results: After ovarian detorsion, until 72 hours after its torsion, reliable reversible restoration of the structural components of the ovary is determined as a positive consequence of the effect of the correction factor (detorsion). Conclusions: The data obtained in the experiment showed that there was a discrepancy between the macroscopic features of the twisted uterine appendages and the microscopic changes in their morphological examination. Despite the presence of external signs of necrosis in the tissue of the uterine appendages, after the detorsion and the restoration of blood flow in them, studies have shown the possibility of performing organ-saving surgical operations in the torsion of the uterine appendages.