Browsing Кафедра фармацевтичної хімії by Title

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Analysis of amino acids content in the plant components of the antidiabetic herbal mixture by GC-MS

Savych, A.; Marchyshyn, S.; Mosula, L.; Bilyk, O.; Humeniuk, I.; Davidenko, A. (Pharmacia, 2022)

Medicinal plants and their combinations due to the wide range of biologically active substances can influence on various links of the pathogenetic mechanism of development of DM type 2 and its complications. One of such ...
Analysis of carbohydrates content in the plant components of antidiabetic herbal mixture by GC-MS

Savych, A.; Duchenko, M.; Shepeta, Y.; Davidenko, A.; Polonets, O. (Pharmacia, 2021)

Medicinal plants and their combinations due to the wide range of biologically active substances can influence on various links of the pathogenetic mechanism of development of diabetes mellitus and its complications. One ...
Analysis of carboxylic acids of Astragalus dasyanthus Pall. herb

Khvorost, O.; Zudova, Y.; Budniak, L.; Slobodianiuk, L.; Kramar, H.; Palamarchuk, O.; Ocheretniuk, A. (Pharmacia, 2023-08-17)

One of the fundamental issues in modern pharmacy is the expansion of the range of medications based on plant-derived raw ma terials with specific targeted effects. An example of such a plant is the woolly-flowered milkvetch ...
Analysis of inulin and fructans in Taraxacum officinale L. roots as the main inulin-containing component of antidiabetic herbal mixture

Savych, A.; Bilyk, O.; Vaschuk, V.; Humeniuk, I. (Pharmacia, 2021)

Herbs and their combinations due to the wide range of biologically active substances can influence on various links of the pathogenetic mechanism of development of diabetes mellitus and its complications. One of such ...
Antimicrobial properties of a new polymeric material based on poly(2-hydroxyethyl methacrylate)

Chornopyshchuk, R.; Nagaichuk, V.; Gerashchenko, I.; Nazarchuk, H.; Kukolevska, O.; Chornopyshchuk, N.; Sidorenko, S. (Acta Biomed, 2022)

Background and aim. Оne of the promising areas is the development of synthetic wound dressings with programmed release of active substances that can affect various elements in the pathogenesis of the wound process. The ...
Antioxidant activity in vitro of antidiabetic herbal mixtures

Savych, A.; Mazur, O. (Pharmacologyonline, 2021)

Medicinal plants and their combinations due to the wide range of biologically active substances can influence on various links of the pathogenetic mechanism of development of diabetes mellitus and its complications. One ...
Changes in the quantitative characteristics of the Ukrainian market of tear replacement products for dry eye disease over 2016-2019

Sakovych, V. M.; Tomashevska, Yu. O.; Makarenko, O. V.; Kryvoviaz, O. V.; Garnyk, M. S. (2022)

Background: Management of dry eye syndrome (DES) is a current medical, pharmaceutical and social issue both globally and in Ukraine. Purpose: To assess changes in quantitative characteristics of the Ukrainian market of ...
Current economical, social aspects of health technologies for preterm birth and real world data of drug prescriptions in Ukraine

Maksymovych, N. M.; Zalis’ka, O. M.; Mudrak, I. H. (2016)

Improving the quality of life and health of pregnant women and their rational pharmacotherapy are the main objectives of WHO. Ukraine occupies 72 place in terms of motherhood in the world. We have analyzed and compared the ...
Determination of amino acids content in two samples of the plant mixtures by GC-MS

Savych, A.; Marchyshyn, S.; Harnyk, M.; Kudria, V.; Ocheretniuk, A. (2021)

Due to the wide range of biologically active substances, the plant mixtures can influence the development of diabetes mellitus and its complications. Amino acids attract particular attention due to their ability to stimulate ...
Development of new C, S, N-containing plastic lubricants based on products from industrial waste integrated processing

Ranskiy, A.; Sandul, O.; Gordienko, O.; Didenko, N.; Titov, T. (Eastern-European Journal of Enterprise Technologies, 2024)

The object of this research is the integrated processing of industrial waste from various indus tries, which makes it possible to reduce the use of material and energy resources and improve the ecological state of the ...
Electrical properties of the (copper, dysprosium)-containing complex compound

Semenov, A.; Martyniuk, V.; Evseeva, M.; Osadchuk, O.; Semenova, O.; Yushchenko, T. (2024)

A new semiconductor material tetrakis-µ3-(methoxy)(methanol)-pentakis(acetylacetonato) (tricopper(II), dysprosium(III)) (I) was synthesized, with the following composition:[Cu3Dy(AA)5(OCH3)4CH3OH], where HAA=H3C–C(O)–CH2–C(O)–CH3. ...
Electrical properties of the nanocomposite (copper, samarium)-containing complex compound

Semenov, A. O.; Martyniuk, V. V.; Evseeva, M. V.; Osadchuk, O. V.; Semenova, O. O. (2022)

A new semiconductor material tetrakis-µ3-(methoxo)(methanol)-pentakis (acetylacetonate)(tricopper(II), samarium(III)) (I) with composition [Cu3Sm(AA)5(OCH3)4CH3OH], where HAA = H3C–C(O)–CH2–C(O)–CH3 has been synthesized. ...
Evaluation of antioxidant activity of 1, 2, 4-triazole derivatives with morpholine moiety

Shcherbyna, R.; Pruhlo, Y.; Duchenko, M.; Kulagina, M.; Kudria, V.; Vashchuk, V. (Hacettepe University Journal of the Faculty of Pharmacy, 2022)

The aim of the work was to study the antioxidant activity of 4-R- 3-(morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. ...
Histological study of a corrective influence of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio) acetate on the state of rats liver under conditions of acute immobilization stress

Safonov, A.; Demianenko, D.; Vashchyk, Y.; Larianovska, Y.; Lytkin, D.; Shcherbyna, R.; Ocheretniuk, A.; Romanova, S. (2022)

Objective: The aim of the work was the histological study of a corrective influence of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl) thio) acetate on the state of rats liver under conditions of acute ...
Hydrophilic/hydrophobic nanocomposition for wound care and method of its manufacturing and use

Chepliaka, O. M.; Gerashchenko, I. I.; Stepanyuk, K. O.; Pakhlov, E. M.; Tausch, A. (2019)

Hydrophilic/hydrophobic composition Pathelen® which contains nanosized silica (Aerosil 300), hydrophobic silica (Aerosil R972 Pharma) and benzalkonium chloride serves as an effective mean for the topical treatment of wounds. ...
Hydrophilic/hydrophobic wound care preparation based on the nanoscale silica: physicochemical and technological aspects

Gerashchenko, I. I.; Stepanyuk, K. О.; Chepliaka, O. М.; Borysenko, M. V.; Pakhlov, E. M.; Klyuchkov, D. G.; Vinogradova, K. G. (Chemistry, Physics and Technology of Surface, 2022)

Неaling of infected ulcers and wounds, particularly in older people, is a serious problem in modern surgery. As a result of many years efforts, we have created an innovative wound care composition that has high absorptive, ...
In vitro anticancer activity screening of Iridaceae plant extracts

Mykhailenko, O.; Lesyk, R.; Finiuk, N.; Stoika, R.; Yushchenko, T.; Ocheretniuk, A.; Vaschuk, V.; Mishchenko, V.; Georgiyants, V. (2020)

The different effects on human tumor cells (MCF-7, HepG2, HCT116, HeLa, HL-60, and HaCaT) for Ukrainian plant extracts have been examined for the first time. The extracts were from Crocus sativus (stigma, flowers, leaves, ...
The influence of physical quantities on electrical parameters of heterometallic μ-methoxy (copper (II), bismuth (III)) acetylacetonate

Semenov, A. O.; Martyniuk, V. V.; Evseeva, M. V.; Osadchuk, O. V.; Osadchuk, I. O. (Journal of Nano- and Electronic Physics, 2023)

The paper presents a technique for obtaining the complex μ-methoxy (copper (II), bismuth (III)) acetylacetonate, Cu3Bi(AA)4(OCH3)5, where HAA = H3C–C(O)–CH2–C(O)–CH3, and results of studying the electrical parameters of ...
Mathematical simulation of a microelectronic transducer with frequency output for measuring the induction of the magnetic field

Osadchuk, A. V.; Osadchuk, I. A.; Martyniuk, V. V.; Krylik, L. V.; Evseeva, M. V. (Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022)

A new magnetically sensitive element based on the synthesized semiconductor material has been developed. A method for the synthesis of a complex compound has been developed tetrakis-μ3-(methoxo) (methanol)-pentakis ...
Methyl 4‐Hydroxy‐2,2‐Dioxo‐1H‐2λ6,1‐Benzothiazine‐ 3‐Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics

Ukrainets, I. V.; Petrushova, L. A.; Shishkina, S. V.; Sidorenko, L. V.; Alekseeva, T. V.; Torianyk, I. I.; Davidenko, A. A. (Scientia Pharmaceutica, 2020)

In order to identify new regularities of the “structure–analgesic activity” relationship in the series of 2,1‐benzothiazine derivatives, the synthesis of methyl 4‐hydroxy‐2,2‐dioxo‐1H‐2λ6,1‐ benzothiazine‐3‐carboxylate ...

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