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dc.contributor.author Dudnyk, V. M. en
dc.contributor.author Kutsak, O. V. en
dc.date.accessioned 2019-01-31T08:35:25Z
dc.date.available 2019-01-31T08:35:25Z
dc.date.issued 2017
dc.identifier.citation Dudnyk V. M. Features prevalence of polymorphism lle50Val gene IL4RA in patients with bronchial asthma and healthy children school age Vinnichina / V. M. Dudnyk, O. V. Kutsak // Journal of Education, Health and Sport. - 2017. - № 7(5). - P. 934-943. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/3314
dc.description.abstract Homozygous genotype A / A Vinnichiny among school children suffering from asthma occurs in 4.34 times (p <0,05) more often and genotype G / G - 4.2 times (p <0,05) less compared to practically healthy children with prevalence 1.6 times allele a carriers (p <0,05), respectively, carrier genotype a / a and a allele is associated with the development of asthma and is a marker of increased risk of disease, and the presence of the genotype G / G and allele G - "unfavorable" to the development of bronchial asthma. The distribution of the frequency of genotypes for the Ile50Val polymorphism of the IL4RA gene is independent of sex and indicates a collision lshennya heterozygous genotype A / G patients among boys in 1.84 times, and among girls - by 1.3 times compared with native homozygous genotype A / A (p <0,001) and, respectively, 8.74 and 9 times - compared with a mutant genotype G / G (p <0.001). en
dc.subject bronchial asthma en
dc.subject polymorphism of gene IL4RA en
dc.subject children en
dc.title Features prevalence of polymorphism lle50Val gene IL4RA in patients with bronchial asthma and healthy children school age Vinnichina en
dc.type Article en


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