Comparative analysis of CT-sizes of thalamus in apparently healthy young men and women in age and somatotypological aspect

Abstract

Summary. A detailed and comprehensive study of the ratio of thalamus size to somatotype and age is extremely relevant, as even minor variations may be crucial in diagnosing the development of cerebrovascular pathology. The aim of the study – to compare and analyze the age and somatotypological changes in Ct-sizes of thalamus in apparently healthy young men and women of the podilia region in ukraine. Materials and Metohods. 82 apparently healthy boys and 86 girls were selected among directed by doctors to CT examinations youths aged from 17 to 21 and girls aged from 16 to 20 years in the third generation residents of Podilia region of Ukraine with suspected brain disease in which the diagnosis was not confirmed, after the additional test screening assessment of health (using a special questionnaire). Committee on Bioethics Vinnytsia National Medical University (protocol no. 10 dated 21.11.2013) found that studies fully satisfy the basic bioethical standards of the Helsinki Declaration, the European Convention on Human Rights and Biomedicine (1977) and the relevant provisions of the WHO and Ministry of Health Ukraine number 281 of 01.11.2000. CT brain research performed using spiral computed tomography “Select SP” company ELscint (Israel) in the horizontal position of the patient on the back, head forward on a special stand for the head. Morphometry included definition of longitudinal and transverse sizes of the right and left thalamus at the level of T5. In all boys and girls anthropometric survey was conducted according to V. V. Bunak scheme in modification of P. P. Shaparenko. To evaluate the somatotype used scheme of J. l. Carter, B. H. Heath. Statistical analysis of the results conducted in the package STATISTICA 6.1 using nonparametric methods. Results and Discussion. In this work presented results boundaries of percentile scope and comparison of CT-sizes of thalamus in apparently healthy young men and women in Podilia region of Ukraine in age and somatotypological aspect. In young men, when dividing into different age groups, smaller values of the transverse size of thalamus are set in 19 years of age than those in 17 and 18 years of age; and when distributed into different somatotypes – larger sizes are in the representatives of the median intermediate and ectomorphic somatotype than in the mesomorphs and ectomesomorphs. In girls, when dividing into different age groups, smaller values are found for most sizes of thalamus in 18 and 20 year-olds than in other age groups; and when dividing into different somatotypes – larger sizes are in the mesomorphic somatotype than endomorphs, endo-mesomorphs and girls of the middle intermediate somatotype. Analysis of the data obtained, taking into account the distribution of somatotypes in different age groups of practically healthy young men and girls, indicates a greater impact of the features of the body structure on the size of the thalamus than age and gender. Conclusions. the comparison of sizes of the thalamus between the different age and somatotypological groups of apparently healthy young men or women from Podilia region of Ukraine supports the hypothesis of academician Nykytyuk about greater impact of type of body structure on the state of various morphological and functional parameters of the body (including the size of the thalamus) than age of and gender.