Наукові публікації каф. фармації: останні внесення

Відображені елементи 21-40 з 95

Electrolysis as a Universal Approach for Isolation of Diverse Chitin Scaffolds from Selected Marine Demosponges †

Nowacki, K.; Galiński, M.; Fursov, A.; Voronkina, A.; Meissner, H.; Petrenko, I.; Stelling, A. L.; Ehrlich, H. (2022)

Three-dimensional chitinous scaffolds often used in regenerative medicine, tissue engineering, biomimetics and technology are mostly isolated from marine organisms, such as marine sponges (Porifera). In this work, we report ...
Marine biomimetics: bromotyrosines loaded chitinous skeleton as source of antibacterial agents

Muzychka, L.; Voronkina, A.; Kovalchuk, V.; Smolii, O. B.; Wysokowski, M.; Petrenko, I.; Youssef, D. T. A.; Ehrlich, I.; Ehrlich, H. (2021)

The marine sponges of the order Verongiida (Demospongiae: Porifera) have survived on our planet for more than 500 million years due to the presence of a unique strategy of chemical protection by biosynthesis of more than ...
Determination of amino acids content in two samples of the plant mixtures by GC-MS

Savych, A.; Marchyshyn, S.; Harnyk, M.; Kudria, V.; Ocheretniuk, A. (2021)

Due to the wide range of biologically active substances, the plant mixtures can influence the development of diabetes mellitus and its complications. Amino acids attract particular attention due to their ability to stimulate ...
Assessment of the effect of various cerebroprotectors on the dynamics of cerebral and central hemodynamics in traumatic brain injury in rats

Semenenko, S. I.; Khodakivskyi, O. A.; Semenenko, A. I.; Semenenko, O. M. (2020)

Now the issue regarding the choice of effective cerebroprotective agents for traumatic brain injury (TBI) remains insufficiently studied.Aim. To assess the effect of using the adamantane derivative 1-adamantylethyloxa-3- ...
Study of the seasonal dynamics tendencies of sales of substitution therapy medications for dry-eye syndrome treatment in Ukraine

Tomashevska, Yu. O.; Kryvoviaz, O. V.; Makarenko, O. V.; Koval, V. M. (2022)

The purpose of the article was to study the seasonality of retail sales of substitution therapy medications for dry eye syndrome treatment over the period of five years (2016-2020) in comparison with the annual monthly ...
Changes in the quantitative characteristics of the Ukrainian market of tear replacement products for dry eye disease over 2016-2019

Sakovych, V. M.; Tomashevska, Yu. O.; Makarenko, O. V.; Kryvoviaz, O. V.; Garnyk, M. S. (2022)

Background: Management of dry eye syndrome (DES) is a current medical, pharmaceutical and social issue both globally and in Ukraine. Purpose: To assess changes in quantitative characteristics of the Ukrainian market of ...
Substantiation of substitution therapy medication for dry eye syndrome treatment in patients using contact lens vision correction

Kryvoviaz, O. V.; Tomashevska, Yu. O.; Toziuk, O. Iu.; Kudria, V. V.; Balanchuk, T. I. (2022)

Objective: The aim: To substantiate the selection of a substitution therapy medication for dry eye syndrome treatment in patients wearing different kinds of contact lenses. Patients and methods: Materials and methods: A ...
Bioaerosols on the atmospheric super highway: An example of long distance transport of Alternaria spores from the Pannonian Plain to Poland

Grewling, M. D.; Chłopek, K.; Grinn-Gofroń, A.; Gwiazdowska, J.; Siddiquee, A.; Ianovici, N.; Kasprzyk, I.; Wójcik, M.; Lafférsová, J.; Majkowska-Wojciechowska, B.; Myszkowska, D.; Rodinkova, V.; Bortnyk, M.; Malkiewicz, M.; Piotrowska-Weryszko, K.; Sulborska-Różycka, A.; Rybniček, O.; Ščevková, J.; Šikoparija, B.; Skjøth, C. A.; Smith, M.; Bogawski, P. (2022)

Alternaria spores are pathogenic to agricultural crops, and the longest and the most severe sporulation seasons are predominantly recorded in rural areas, e.g. the Pannonian Plain (PP) in South-Central Europe. In Poland ...
Molecular Profile Sensitization to House Dust Mites as an Important Aspect for Predicting the Efficiency of Allergen Immunotherapy

Rodinkova, V. V.; Yuriev, S. D.; Kryvopustova, M. V.; Mokin, V. B.; Kryzhanovskyi, Y. M.; Kurchenko, A. I. (2022)

House dust mite (HDM) allergens are considered to be one of the most common causes of asthma and allergic rhinitis in the world. Cysteine proteases Der p 1 and Der f 1 (group 1) and also NPC 2 family proteins Der p 2 and ...
Effect of apple pectin on the histrostructure of the liver under acute and chronic alcohol intoxication

Hainiuk, M. B.; Kalko, K. O.; Hutsol, V.; Drogovoz, S. M.; Bulgacova, I.; Khomenko, V. M.; Kovpak, A.; Tsubanova, N. A. (2021)

Alcohol is perhaps the oldest of all known psycho-active substances, which is widely used by the population of the globe in large quantities. Treatment of acute poisoning in all countries is carried out according to ...
Manifestation of toxic action of paracetamol in female and male rats depending on the circadian rhythms of liver activity

Kalko, K. O.; Drogovoz, S. M.; Koyro, O. O.; Tsubanova, N. A.; Toziuk, O. Yu.; Lenha, E. L.; Bahan, S. O.; Borysiuk, I. Yu. (2021)

Today, the toxicity of paracetamol is very common, this is due to both the widespread availability of the drug and the misconception of its high safety. Paracetamol poisoning is the most common cause of severe acute liver ...
Chronopharmacological study of hepatoprotective activity of the drug «Antral®»

Kalko, K. O.; Zacharko, N. V.; Drogovoz, S. M.; Dehtiarova, K. O.; Gerush, O. V.; Toziuk, O. Yu.; Barus, M. (2021)

In recent years, in chronopharmacology, daily monitoring of biorhythms has become increasingly important as much more informative and clinically relevant. Antral - as a hepatoprotective agent has been successfully used in ...
Progress in chitin analytics

Tsurkan, M. V.; Voronkina, A.; Khrunyk, Y.; Wysokowski, M.; Petrenko, I.; Ehrlich, H. (2021)

Chitin is the second most abundant biopolymer and functions as the main structural component in a variety of living organisms. In nature, chitin rarely occurs in a pure form, but rather as nanoorganized chitin-proteins, ...
Investigation of the rheological properties of ointment bases as a justification of the ointment composition for herpes treatment

Ivko, T.; Hrytsenko, V.; Kienko, L.; Bobrytska, L.; Kukhtenko, H.; Germanyuk, T. (2021)

Objectives: Combinatorial drugs are among the leading pharmacotherapeutic agents, including those used for the treatment of herpetic infections, which require complex treatment. We have developed a soft dosage form of ...
Abundance of Ganoderma sp. in Europe and SW Asia: modelling the pathogen infection levels in local trees using the proxy of airborne fungal spore concentrations

Grinn-Gofroń, A.; Bogawski, P.; Bosiacka, B.; Nowosad, J.; Camacho, I.; Sadyś, M.; Skjøth, C. A.; Pashley, C. H.; Rodinkova, V.; Çeter, T.; Traidl-Hoffmann, C.; Damialis, A. (2021)

Ganoderma comprises a common bracket fungal genus that causes basal stem rot in deciduous and coniferous trees and palms, thus having a large economic impact on forestry production. We estimated pathogen abundance using ...
Extreme Biomimetics: Designing of the First Nanostructured 3D Spongin–Atacamite Composite and its Application

Tsurkan, D.; Simon, P.; Schimpf, C.; Motylenko, M.; Rafaja, D.; Roth, F.; Inosov, D. S.; Makarova, A. A.; Stepniak, I.; Petrenko, I.; Springer, A.; Langer, E.; Kulbakov, A. A.; Avdeev, M.; Stefankiewicz, A. R.; Heimler, K.; Kononchuk, O.; Hippmann, S.; Kaiser, D.; Viehweger, C.; Rogoll, A.; Voronkina, A.; Kovalchuk, V.; Bazhenov, V. V.; Galli, R.; Rahimi-Nasrabadi, M.; Molodtsov, S. L.; Rahimi, P.; Falahi, S.; Joseph, Y.; Vogt, C.; Vyalikh, D. V.; Bertau, M.; Ehrlich, H. (2021)

The design of new composite materials using extreme biomimetics is of crucial importance for bioinspired materials science. Further progress in research and application of these new materials is impossible without understanding ...
Comparative analysis of the fatty acid composition of raw material of rye (Khamarka variety) and barley (shedevr variety) of ukrainian selection

Tartynska, G.; Zhuravel, І.; Kyslychenko, V.; Hutsol, V. (2021)

Sowing rye (Secale cereale L.) and common barley (Hordéum vulgáre L.) are annual herbaceous plants of the Poaceae family, they are widely cultivated in many countries around the world as cereals and fodder crops. Sufficient ...
High Ambrosia pollen concentrations in Poland respecting the long distance transport (LDT)

Stępalska, D.; Myszkowska, D.; Piotrowicz, K.; Kluska, K.; Chłopek, K.; Grewling, Ł.; Lafférsová, J.; Majkowska-Wojciechowska, B.; Malkiewicz, M.; Piotrowska-Weryszko, K.; Puc, M.; Rodinkova, V.; Rybníček, O.; Ščevková, J.; Voloshchuk, K. (2020)

High Ambrosia pollen concentrations in Poland rather rarely come from the local sources. The aim of this study was to define the temporal and spatial differences of the high Ambrosia pollen concentrations by creating models ...
Marine biomaterials: Biomimetic and pharmacological potential of cultivated Aplysina aerophoba marine demosponge

Binnewerg, B.; Schubert, M.; Voronkina, A.; Muzychka, L.; Wysokowski, M.; Petrenko, I.; Djurović, M.; Kovalchuk, V.; Tsurkan, M.; Martinovic, R.; Bechmann, N.; Fursov, A.; Ivanenko, V. N.; Tabachnick, K. R.; Smolii, O. B.; Joseph, Y.; Giovine, M.; Bornstein, S. R.; Stelling, A. L.; Tunger, A.; Schmitz, M.; Taniya, O. S.; Kovalev, I. S.; Zyryanov, G. V.; Guan, K.; Ehrlich, H. (2020)

Marine demosponges of the Verongiida order are considered a gold-mine for bioinspired materials science and marine pharmacology. The aim of this work was to simultaneously isolate selected bromotyrosines and unique chitinous ...
Functionalization of 3D chitinous skeletal scaffolds of sponge origin using silver nanoparticles and their antibacterial properties

Machałowski, T.; Czajka, M.; Petrenko, I.; Meissner, H.; Schimpf, C.; Rafaja, D.; Ziętek, J.; Dzięgiel, B.; Adaszek, Ł.; Voronkina, A.; Kovalchuk, V.; Jaroszewicz, J.; Fursov, A.; Rahimi-Nasrabadi, M.; Stawski, D.; Bechmann, N.; Jesionowski, T.; Ehrlich, H. (2020)

Chitin, as one of nature’s most abundant structural polysaccharides, possesses worldwide, high industrial potential and a functionality that is topically pertinent. Nowadays, the metallization of naturally predesigned, 3D ...

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