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Перегляд Наукові публікації каф. фармацевтичної хімії за назвою

Перегляд Наукові публікації каф. фармацевтичної хімії за назвою

Відображені елементи 18-37 з 57

Mathematical simulation of a microelectronic transducer with frequency output for measuring the induction of the magnetic field

Osadchuk, A. V.; Osadchuk, I. A.; Martyniuk, V. V.; Krylik, L. V.; Evseeva, M. V. (Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022)

A new magnetically sensitive element based on the synthesized semiconductor material has been developed. A method for the synthesis of a complex compound has been developed tetrakis-μ3-(methoxo) (methanol)-pentakis ...
Methyl 4‐Hydroxy‐2,2‐Dioxo‐1H‐2λ6,1‐Benzothiazine‐ 3‐Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics

Ukrainets, I. V.; Petrushova, L. A.; Shishkina, S. V.; Sidorenko, L. V.; Alekseeva, T. V.; Torianyk, I. I.; Davidenko, A. A. (Scientia Pharmaceutica, 2020)

In order to identify new regularities of the “structure–analgesic activity” relationship in the series of 2,1‐benzothiazine derivatives, the synthesis of methyl 4‐hydroxy‐2,2‐dioxo‐1H‐2λ6,1‐ benzothiazine‐3‐carboxylate ...
Polymeric material with controlled release of antimicrobial agents for medical application

Nagaichuk, V.; Gerashchenko, I.; Chornopyshchuk, R.; Nazarchuk, O.; Kukolevska, O.; Faustova, M.; Burkovskyi, M. (Malaysian Journal of Medicine and Health Sciences, 2022)

Introduction: Nowadays the use of synthetic polymers has become an integral part of modern medicine. Poly(2-hy-droxyethyl methacrylate) has attracted special attention for therapeutic use. The objective of this study was ...
Prospects For the Search For New Biologically Active Compounds Among the Derivatives of the Heterocyclic System of 1,2,4-Triazole

SAMELIUK, Y; KAPLAUSHENKO, A; DIAKOVA, F; OSTRETSOVA, L; NEDOREZANIUK, N; GUTYJ, B (Hacettepe University Journal of the Faculty of Pharmacy, 2022)

The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5. The authors set the task of forming an idea of ...
Role of 4-Thiazolidinone–Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines

Kosińska, K.; Skóra, B.; Holota, S.; Tabęcka-Łonczyńska, A.; Lesyk, R.; Szychowski, A. (Cells, 2024)

Cancer is one of the most important problems of modern societies. Recently, studies have reported the anticancer properties of rosiglitazone related to its ability to bind peroxisome proliferator receptor γ (PPARγ), which ...
Role of ciminalum-4-thiazolidinone hybrids in molecular NF-κB dependent pathways

Szlachcikowska, D.; Tabecka-Łonczy´nska, A.; Holota, S.; Roman, O.; Shepeta, Y.; Lesyk, R.; Szychowsk, A. (International Journal of Molecular Sciences, 2024)

A range of hybrid molecules incorporating the ciminalum moiety in the thiazolidinone ring demonstrate significant anticancer and antimicrobial properties. Therefore, the aim of our study was to evaluate the properties and ...
Study of antimicrobial effect of Сhrysanthemum × hortorum bailey pectoral variety flowers and leaves

Marchyshyn, S.; Polonets, O.; Tkachuk, N.; Nakonechna, S.; Harnyk, M.; Yurkiv, V. (Pharmacology Оnline, 2021)

The aim. The aim of our study was to determine the antimicrobial effect of 10% and 20% aqueous solutions of Chrysanthemum x hortorum Bailey flowers and leaves Pectoral variery. Materials and methods. 10 % and 20 % native ...
Study of hypoglycemic activity of antidiabetic herbal mixture on streptozotocin-nicotinamide-induced rat model of type 2 diabetes

Savych, A.; Polonets, O. (Pharmacologyonline, 2021)

Diabetes is a global problem today, as the number of patients in the world increases sharply every year. Severe complications of diabetes are very dangerous, as they can lead to disability and high mortality. The purpose ...
Study of the morphological and anatomic signs of the flowers of the Chrysanthemum hortorum Bailey sort Pectoral (pharmacognostic analysis)

Marchyshyn, S.; Polonets, O.; Harnyk, M.; Sira, L. (Scientific Journal «ScienceRise: Pharmaceutical Science», 2020)

The aim. To study of the morphological and anatomical features of the structure of inflorescences of Chrysanthemum × hortorum Bailey, variety Pectoral. Materials and methods. The inflorescences of Chrysanthemum × hortorum ...
Study of the Stress-Protective Effect of Sodium 2-((4-amino-5-(thiophen-2-ylmethyl)- 4H-1,2,4-triazol-3-yl)thio)acetate

Safonov, А.; Demianenko, D.; Vashchyk, Y.; Lytkin, D.; Polonets, O.; Kosareva, A.; Morozova, L. (Hacettepe University Journal of the Faculty of Pharmacy, 2024)

The aim was to study the stress-protective effect of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetate (ASP). The analysis of the effect of the sample on the behavior and psycho-emotional state ...
Synthesis and biological activity evaluation of new thiazolidinone-diclofenac hybrid molecules

Shepeta, Y.; Lozynskyi, A.; Sulyma, M.; Nektegayev, I.; Grellier, P.; Lesyk, R. (Phosphorus, Sulfur, and Silicon and the Related Elements, 2020)

A novel series of [2-(2,6-dichlorophenylamino)-phenyl]-acetic acid N -3-(substituted)-4-thiazolidin-5- ylidenemethyl-hydrazide derivatives has been designed and synthesized. The structures of synthesized compounds were ...
Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3H-thiazolo[4,5-b]pyridin-2-ones

Lozynskyi, A.; Konechnyi, Y.; Senkiv, J.; Yushyn, I.; Khyluk, D.; Karpenko, O.; Shepeta, Y.; Lesyk, R. (Scientia Pharmaceutical, 2021)

A series of 5-methyl-7-phenyl-3H-thiazolo[4,5-b]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic ...
Synthesis and evaluation of biological activity of rhodaninepyrazoline hybrid molecules with a 2-(2,6-dichlorophenylamino)- phenylacetamide fragment

Shepeta, Yu. L; Lozynskyi, A.V.; Tomkiv, Z. V.; Grellier, P.; Lesyk, R. B. (Biopolymers and Cell, 2020)

Synthesis of new rhodanine-pyrazoline hybrid molecules with a diclofenac fragment in position 3 using the reactions of heterocyclization and aminolysis with potential antitumor and antitrypanosomal activities. Methods. ...
Synthesis of heterocyclic thioamides and copper(ІІ) сoordination compounds based on them

Ranskiy, A. P.; Didenko, N. O.; Gordienko, O. A. (НУ "Львівська політехніка", 2017)

Arylamides of hetaryl-2-thiocarbonic acid were synthesized via Willgerodt–Kindler modified reaction. The final products were studied by means of chemical analysis, IR- and 1H NMR-spectroscopy. The coordination compounds ...
Synthesis, antimicrobial and antifungal activity of ylidenhydrazides of 2-((4-R-5-R1-4H-1,2,4-TRIAZOL-3-YL)THIO) acetaldehydes

Shcherbyna, R.; Panasenko, O.; Polonets, O.; Nedorezaniuk, N.; Duchenko, M. (Journal of Faculty of Pharmacy of Ankara University, 2021)

Objective: The aim of this work is the synthesis and studying of antimicrobial and antifungal properties of the ylidenhydrazides of 2-((4-R-5-R1-4H-1,2,4-triazol-3-yl)thio)acetaldehydes with the establishment of ...
Synthesis, structure and application of mixed-ligand coordination compounds of copper(ІІ) with substituted thioamides

Ranskiy, A.; Gordienko, O.; Didenko, N.; Titov, T.; Khutko, M. (2020)

New coordination compounds of copper(II) with substituted thioamides of the general formula [Cu(HL6-9)2X2]2 and CuL2 6-9 have been synthesized. The consecutive reaction of nucleophilic substitution/elimination of SN 1 /E1 ...
Technological and biopfarmaceutical aspects of developing the basics of soft medicinal local action

Tarasenko, V.; Pidlisnyy, A.; Koval, A.; Solomennyy, A.; Vaschu, V.; Davtia, L.; Goncharenko, N.; Sakhanda, I.; Naumova, M. (Archives of Pharmacy Practice, 2020)

Extensive clinical experience and experimental data irrefutably prove that local drug treatment of wounds should be built strictly in accordance with those processes that occur at different stages of the wound process, ...
The Influence of Physical Quantities on Electrical Parameters of Heterometallic -Methoxy (Copper (II), Bismuth (III)) Acetylacetonate

Semenov, A; Martyniuk, V; Evseeva, M; Osadchuk, O; Osadchuk, I (Journal of Nano- and Electronic Physics, 2023)

The paper presents a technique for obtaining the complex μ-methoxy (copper (II), bismuth (III)) acetylacetonate, Cu3Bi(AA)4(OCH3)5, where HAA = H3C–C(O)–CH2–C(O)–CH3, and results of studying the electrical parameters of ...
Theoretical basis of creation of soft medicinal products of local application

Tarasenko, V.; Solomennyy, A.; Pidlisnyy, A.; Koval, A.; Vaschuk, V.; Shmatenko, A.; Davtian, L.; Takhtaulova, N.; Sakhanda, I.; Koziko, N.; Shumeiko, M. (Archives of Pharmacy Practice, 2020)

The widespread use of firearms in the cells of military conflicts, modern weapons, bullets, and new-generation devices causes an increase in the number of severe wounds, characterized by significant damage to soft tissues, ...
Thermoresistive properties of (Copper, Neodymium) Acetylacetonate

Osadchuk, A. V.; Martyniuk, V. V.; Evseeva, M. V.; Osadchuk, Ya. A.; Avramchuk, О. Ye. (Physics and chemistry of solid state, 2022)

A new material tetrakis-μ3-(methoxo) (methanol)-pentakis(acetylacetonate) (tricuprum (II), neodymium (III)) methanol (I) was synthesized as [Cu3Nd(AA)5(OCH3)4CH3OH] CH3OH, where HAA = H3C–C(O)–CH2–C(O)–CH3. Based on the ...

Перегляд Наукові публікації каф. фармацевтичної хімії за назвою

Перегляд Наукові публікації каф. фармацевтичної хімії за назвою

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