Discriminative models of the possibility of occurrence and features of the course of alopecia areata in Ukrainian men depending on the features of body structure and size indicators

Abstract

Hair loss in men is not only an aesthetic problem, but can also indicate deeper systemic changes in the body. The increase in the number of cases of such conditions requires a detailed study of the factors that influence their development and course. Researchers pay special attention to the morphofunctional characteristics of the body, which can play a prognostic role in the formation of pathological processes. This opens up prospects for a more personalized approach to the diagnosis and prevention of this pathology. The aim of the study is to build and analyze discriminant models of the possibility of occurrence and features of the course of alopecia areata in young Ukrainian men depending on the features of the structure and body size. A clinical, instrumental and anthropological examination of 81 patients with alopecia areata in young Ukrainian men was conducted. The severity of the disease was determined according to Shutsky I. V. The control group (according to anthropological indicators) consisted of 82 practically healthy young Ukrainian men, whose were taken from the data bank of the scientific research center of the National Pirogov Memorial Medical University. Discriminant models of the possibility of occurrence and features of the course of alopecia areata in dependence on the features of the structure and body size were built in the “Statistica 6.0” license package. It was established that both when dividing Ukrainian men into practically healthy and patients with alopecia areata in general, and when dividing into practically healthy and patients with alopecia areata with different degrees of severity of the disease, reliable (p<0.001) highly informative discriminant models of the possibility of the occurrence of this disease were constructed depending on the features of the structural indicators and body sizes (respectively, the correctness of entering the models of anthropological indicators is 100 % and 77.78 % of cases; Wilks’ Lambda statistics are 0.097 and 0.098). The greatest contribution to the discrimination between practically healthy and patients with alopecia areata in general, and between practically healthy and patients with different degrees of severity of Ukrainian men is shoulder width and the width of the distal epiphysis of the tibia. It is impossible to determine the course of alopecia areata based on anthropometric body parameters. The most common differences in the constructed models include: between the practically sighted and the general group of patients – transverse dimensions of the trunk and pelvis (42.86 %) and longitudinal dimensions of the body (28.57 %); between the practically sighted and patients with alopecia areata with varying degrees of disease severity – longitudinal dimensions of the body (33.33 %)