Modern conservative etiopathogenetic treatment of cervicalintraepithelial neoplasia (literature review)

Abstract

Annotation. We used PubMed, Cochrane Library, Google Scholar databases, mostly referring to publications from the last fiveyears (2016-2020). The long-term persistence of oncogenic types of human papilloma virus is the main etiological factor for cervicalintraepithelial neoplasia (CIN). Prolonged persistence of herpes infection can also have a transformative effect on cervical epithelium.Since this pathology is most often diagnosed in women of reproductive age, the maximum preservation of reproductive function,prevention of perinatal complications requires the search for new conservative CIN treatments aimed at the complete elimination ofviruses and neoplastic cells. The effectiveness of conservative antiviral therapy of CIN I, II without the use of surgical methods hasbeen proved, especially in women who have not fulfilled their reproductive plans. In addition, antiviral therapy during pre- andpostoperative periods contributes to the reduction of complications and relapses in women with severe cervical neoplasia.