Topographic and anatomical justification of the approach to performing intraperitoneal injection

Abstract

Performing intraperitoneal injections in rats is one of the most common and accessible methods of administering drugs and anesthetics in an experiment. In 74 % of cases (32/43), the cecum was located on the right and along the midline. A midline was performed in the laboratory animal from the external opening of the urethra to the xiphoid process. Through the point that divides it in half, a perpendicular was drawn along the left half of the abdomen’s front wall. A bisector formed at an angle of 90° to the inguinal fold was lowered into the left inguinal region. The injection site was defined as a point lying on ½ of the line formed by the bisector of the angle. The proposed technical solution has significant advantages: it justifies the place and point of intraperitoneal injection and reduces the risk of iatrogenic damage to abdominal organs.