To describe demographics, clinical features, and treatment outcomes of patients with highly drug-resistant tuberculosis (TB) in Ukraine, and to evaluate risk factors for an unsuccessful outcome. Data from patients with multi-, preextensively, or extensively drug-resistant TB were collected prospectively from TB dispensaries in 15 out of 24 Ukrainian oblasts (regions) from 2020 to 2021. Treatment outcomes were evaluated using WHO definitions. Risk factors for an nsuccessful outcome were identified using a multivariable logistic regression model.
Ukraine remains a high World Health Organization priority country for drug-resistant tuberculosis (TB). Rifampicin-resistant TB (RR-TB) has a more protracted, more complicated, and more expensive treatment. In 2021, Ukraine ...
Ljungquist, O.; Magda, M.; Giske, C.; Tellapragada, C.; Nazarchuk, O.; Dmytriiev, D.; Thofte, O.; Öhnström, V.; Matuschek, E.; Blom, A.; Riesbeck, K.(International Journal of Medical Microbiology, 2024)
Objectives: Carbapenem- and colistin-resistant Klebsiella pneumoniae were isolated from war victims treated in hospitals in Ukraine. The question was whether these pandrug-resistant K. pneumoniae are pathogenic and capable ...
Bahniuk, N. A.; Faustova, M. O.; Riesbeck, K.; Prokopchuk, Z. M.; Loban, G. I.; Nazarchuk, О. А.(The Medical and Ecological Problems, 2023)
The aimof the study was to determine the correspondence between the carbap-enemase genotype and the phenotypic antimicrobial profiles of P. aeruginosa.Materials and methods.The study included 51 clinical isolates of P. ...