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dc.contributor.author Storozhuk, O. B. en
dc.contributor.author Seleznyova, I. B. en
dc.contributor.author Storozhuk, L. A. en
dc.contributor.author Dovgalyuk, T. V. en
dc.contributor.author Storozhuk, B. G. en
dc.contributor.author Platonova, T. N. en
dc.date.accessioned 2020-12-10T18:37:58Z
dc.date.available 2020-12-10T18:37:58Z
dc.date.issued 2020
dc.identifier.citation Status of pro- and anticoagulant components of hemostasis in patients with stage VD CKD depending on residual renal function / O. B. Storozhuk, I. B. Seleznyova, L. A. Storozhuk [et al.] // Wiadomości Lekarskie. – 2020. – Vol. 73 (8). – P. 1723-1725. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/4992
dc.description.abstract The aim: To study the status of pro- and anticoagulant components of hemostasis in patients with stage VD CKD depending on residual renal function. Materials and methods: 88 patients with stage VD CKD were studied, 16 of them had preserved residual renal function (RRF). Hemostatic parameters – soluble fibrin, D-dimer and protein C – were determined in the patients. Results: Significant increase in soluble fibrin and fibrinogen levels along with depressive reaction of D-dimer and protein C were found in patients with stage VD CKD having lost RRF. Preserved RRF in those patients had positive influence on hemostatic profile, decreasing the degree of hypercoagulation. Conclusions: 1. In long term dialysis patients with stage VD CKD and lost RRF, significantly increased levels in soluble fibrin and fibrinogen along with decreased D-dimer concentration were found, being a key factor in the development of thrombotic complications. 2. There was significant decrease in protein C activity in patients with lost RRF. 3. Preserved RRF in patients with stage VD CKD had positive influence on hemostatic profile. uk_UA
dc.language.iso en en
dc.subject hemostasis en
dc.subject chronic kidney disease (CKD) en
dc.subject residual renal function (RRF) en
dc.title Status of pro- and anticoagulant components of hemostasis in patients with stage VD CKD depending on residual renal function en
dc.type Article en


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