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Overall hemostasis potential of the blood plasma and its relation to some molecular markers of the hemostasis system in patients with chronic renal disease of stage VD

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dc.contributor.author Storozhuk, B. G. en
dc.contributor.author Pyrogova, L. V. en
dc.contributor.author Chernyshenko, T. M. en
dc.contributor.author Kostiuchenko, O. P. en
dc.contributor.author Kolesnikova, I. M. en
dc.contributor.author Platonova, T. M. en
dc.contributor.author Storozhuk, O. B. en
dc.contributor.author Storozhuk, L. O. en
dc.contributor.author Bereznitsky, G. K. en
dc.contributor.author Tsap, P. Yu. en
dc.contributor.author Masenko, O. O. en
dc.contributor.author Makogonenko, E. M. en
dc.contributor.author Lugovskoy, E. V. en
dc.date.accessioned 2020-02-12T10:24:18Z
dc.date.available 2020-02-12T10:24:18Z
dc.date.issued 2018
dc.identifier.citation Overall hemostasis potential of the blood plasma and its relation to some molecular markers of the hemostasis system in patients with chronic renal disease of stage VD / B. G. Storozhuk, L. V. Pyrogova, T. M. Chernyshenko [et al.] // Ukr. Biochem. Journ. - 2018. - Vol. 90, № 5. - P. 60-70. en
dc.identifier.issn 2409-4943
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/4355
dc.description.abstract The values of the coagulation, overall and fibrinolysis potentials were estimated by the method of the global potential of Blomback M., as well as the values of concentrations of molecular markers of the hemostasis system: soluble fibrin (sf), D-dimer, fibrinogen (Fg) and protein C (88 patients, 52 of them men, 36 women). It was shown that hemostasis system activity in women plasma is higher than that in men plasma. The division of patients into 3 groups, depending on the concentration of sf: less than normal – sf ≤ 3, about norm – 3 < sf < 4 and more than norm – sf > 4 μg/ml, allowed establishing the growth of the parameters of both the hemostatic potential and concentrations of molecular markers in accordance with concentration of sf in the groups of patients. Paerson’s correlation analysis of the relationship between the parameters of the hemostasis potential and concentrations of molecular markers revealed an increase in the correlation relationship to the strong and very strong between the parameters of coagulation, fibrinolysis and protein C systems with an increase in the concentration of soluble fibrin in plasma of patients. en
dc.language.iso en en
dc.subject hemostasis potential of plasma en
dc.subject soluble fibrin en
dc.subject D-dimer en
dc.subject fibrinogen en
dc.subject protein C en
dc.title Overall hemostasis potential of the blood plasma and its relation to some molecular markers of the hemostasis system in patients with chronic renal disease of stage VD en
dc.title.alternative Загальний гемостатичний потенціал плазми крові і його зв’язок із деякими молекулярними маркерами системи гемостазу у хворих на хронічні захворювання нирок VD стадії uk_UA
dc.type Article en


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