Репозиторій Вінницького національного медичного університету імені М. І. Пирогова

Soluble vascular cell adhesion molecule-1 level in patients with anthiphospolipid syndrome: its association with disease activity and endothelium dysfunction

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dc.contributor.author Segeda, Iu. en
dc.contributor.author Shevchuk, S. en
dc.contributor.author Kuvikova, I. en
dc.date.accessioned 2020-02-11T10:31:55Z
dc.date.available 2020-02-11T10:31:55Z
dc.date.issued 2012
dc.identifier.citation Segeda Iu. Soluble vascular cell adhesion molecule-1 level in patients with anthiphospolipid syndrome: its association with disease activity and endothelium dysfunction / Iu. Segeda, S. Shevchuk, I. Kuvikova // Rheumatology. – 2012. – Vol. 51, issue suppl. 3, ill.140. – P. 181. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/4346
dc.description.abstract The aim of this observation case was to investigate the link of soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration with disease activity and endothelium dysfunction as an early marker of atherosclerosis. 67 patients with anthiphospolipid syndrome (APS) were studied: 21 (31.3%) with primary APS (PAPS), 19 (28.4%) with APS associated with systemic lupus erythematosus (APS-SLE), 27 (40.3%) with SLE without APS and 26 age and sex matched healthy controls (HC). According to this data it might be hypothesized that increase sVCAM-1 level is a marker of endothelium dysfunction in patients with APS especially in presence of high disease activity. en
dc.language.iso en en
dc.subject anthiphospolipid syndrome en
dc.subject systemic lupus erythematosus en
dc.subject soluble vascular cell adhesion molecule-1 en
dc.subject endothelium dysfunction en
dc.subject atherosclerosis en
dc.title Soluble vascular cell adhesion molecule-1 level in patients with anthiphospolipid syndrome: its association with disease activity and endothelium dysfunction en
dc.type Thesis en


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