Репозиторий Винницкого национального медицинского университета имени Н. И. Пирогова

Immune status of patients with frontal basilar trauma having BC ‘Syntekost’ applied in the surgical treatment. Report 1. The state of the of the systemic cellular and humoral immunity factors of the patients with frontal basilar trauma the acute posttraumatic period prior to surgical treatment

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dc.contributor.author Kishchuk, V. en
dc.contributor.author Bondarchuk, O. en
dc.contributor.author Dmitrenko, I. en
dc.contributor.author Lobko, K. en
dc.contributor.author Grytsun, Y. en
dc.contributor.author Timchenko, M. en
dc.contributor.author Datsiuk, O. en
dc.contributor.author Bevz, H. en
dc.date.accessioned 2019-12-19T11:50:12Z
dc.date.available 2019-12-19T11:50:12Z
dc.date.issued 2019
dc.identifier.citation Immune status of patients with frontal basilar trauma having BC ‘Syntekost’ applied in the surgical treatment. Report 1. The state of the of the systemic cellular and humoral immunity factors of the patients with frontal basilar trauma the acute posttraumatic period prior to surgical treatment / V. Kishchuk, O. Bondarchuk, I. Dmitrenko [et al.] // Wiadomości Lekarskie.- Wydawnictwo Aluna, 2019.- Tom (Vol) LXXII, nr (№) 9.- cz II.- P. 1791-4. http://wl.medlist.org/2019_09_34/ en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/4220 en
dc.description.abstract OBJECTIVE: Introduction: At present biocomposite materials are used in the surgical treatment of frontal bone fracture. They improve osteogenesis, reduce the number of complications. Immunologic aspects of application of these materials are studied insufficiently, therefore this report presents the results of immunoassay of patients with frontal bone fracture in the proximate posttraumatic period before implanting preparation "Syntekost". The aim: To define the role of immune mechanisms in the realization of the biocomposite material's positive influence on the development of effective posstraumatic rehabilitation schemes. PATIENTS AND METHODS: Materials and methods: 16 patients with frontal bone fracture (FBF) were examined on admission to the Otolaryngology Clinics of Vinnitsa Region Hospital. Additionally, 10 patients of the similar age were examined as a control group. The content of cells with markers of surface antigens-CD3,14,16,20,25, concentration of immunoglobulins of classes M,G,A,E, С4 complement component and lactoferrin was determined in blood. Immunoenzyme methods were applied. Nonparametric Wilcoxon - Mann - Whitney test, computer programme WIN Pepi were used for statistical measurements. RESULTS: Results: A decrease in the level of IgM in comparison with practically healthy donors and an increase in the concentration of lactoferrin were identified as humoral immunity factors of patients with frontal basilar trauma. The most significant deviation in the peripheral blood cellular makeup in CD-markers was an increase in cells with markers CD14 and CD16. CONCLUSION: Conclusions: The level of cells and prodefensin-lactoferrin that maintain inborn immunity increases and the concentration of coarse defensive protein decreases in the initial period after frontal bone fracture, which must be taken into consideration during post-surgical treatment. en
dc.language.iso en en
dc.subject trauma frontal basilar en
dc.subject BC ‘Syntekost’ en
dc.subject factors immunity systemic cellular en
dc.subject factors immunity systemic humoral en
dc.subject period acute posttraumatic en
dc.subject treatment surgical en
dc.title Immune status of patients with frontal basilar trauma having BC ‘Syntekost’ applied in the surgical treatment. Report 1. The state of the of the systemic cellular and humoral immunity factors of the patients with frontal basilar trauma the acute posttraumatic period prior to surgical treatment en
dc.type Article en


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