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Modeling the possibility of occurrence of overactive bladder in women of different ages, depending on anthropo-somatotypological indicators or hormonal background with the help of discriminant analysis

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dc.contributor.author Kostyuk, I. Yu. en
dc.contributor.author Chayka, G. V. en
dc.contributor.author Storozhuk, M. S. en
dc.contributor.author Tarasiuk, O. K. en
dc.date.accessioned 2019-02-05T16:25:41Z
dc.date.available 2019-02-05T16:25:41Z
dc.date.issued 2018
dc.identifier.citation Modeling the pissibility of occurrence of overactive bladder in women of different ages, depending on anthropo-somatotypological indicators or hormonal background with the help of discriminant analysis / I. Yu. Kostyuk, G. V. Chayka, M. S. Storozhuk, O. K. Tarasiuk // Biomedical and biosocial anthropology. - 2018. - № 31. - P. 73-79. en
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/3323
dc.description.abstract One of the most important problems of modern urogynecology is the improvement of the treatment-diagnostic algorithm and prevention of overactive bladder syndrome (OAB). The purpose of the work is to construct and analyze discriminant models of the possibility of OAB occurrence in pregnant women of different age groups depending on the characteristics of anthropo-somatotypological indicators or hormonal background. 75 pregnant women with clinical signs of OAB syndrome and 60 healthy pregnant women had hormonal screening in the 1st and 3rd trimester of pregnancy and at 16 weeks postpartum using radioimmunoassay and immune enzyme methods (estradiol, progesterone, thyroid stimulating hormone and testosterone levels were determined). The anthropometry was carried out according to the method of V. V. Bunak, the components of the somatotype were determined according to the method of J. Carter and B. Heath, as well as the components of the body composition according to the methodofJ. Matiegka and the American Institute of Nutrition (AIN). By age, all pregnant women were divided into 3 subgroups: I - from 17 to 25 years, II - from 26 to 35 years, III - from 36 to 41 years. A discriminant analysis of the possibility of OAB occurrence, depending on the anthropo-somatotypological or hormonal indices in women of different age groups, was conducted using the licensing program "Statistica 5.5". When taken into account anthropo-somatotypological indices in women aged from 17 to 25 years, the model is correct in 86.7% of cases; in women aged from 26 to 35 years - in 90.9% of cases; in women between the ages of 36 and 41 years - in 89.3% of cases. Between healthy and OAB patients, women aged from 17 to 25 years discriminating variables are the width of the distal epiphysis of the shoulder (which has the greatest contribution to discrimination), conjugata externa, the muscle component of the body weight by AIN and the forearm's girth in the upper third; women from 26 to 35 years - dist. Intertrochanterica, the width of the distal epiphyses of the forearm (the greatest contribution to discrimination), hip circumference, conjugata externa, mesomorphic component of the somatotype according to by Heath-Carter, fat mass component of the body by Matiegka, the forearm's girth in the upper third and the shoulder girth; women of age from 36 to 41 years - the width of the distal epiphysis of the leg (which has the greatest contribution to discrimination) and the length of the body. In general, the aggregate of all variables has a low level of discrimination between healthy and sick with OAB women between the ages of 17 and 25 (Wilkes Lambda statistics = 0.531; F = 5.521; p <0.01) and 36-41 years (Wilkes Lambda statistics = 0.445; F = 15.62; p <0.001), while among women between the ages of 26 and 35 - the average level of discrimination (Wilkes Lambda statistics = 0.386; F = 13.52; p <0.001). When taken into account characteristics of the hormonal background in women of all ages, the model is correct in 100%of cases. Between healthy and OAB patients, of17-25years age, discriminant variables are estradiol levels at 16 weeks of postpartum (with the largest contribution to discrimination) and prolactin levels in the first trimester of pregnancy; women aged from 26 to 35 years - estradiol levels at 16 weeks of postpartum (the most contributing to discrimination), testosterone in the third trimester of pregnancy, estradiol in the third trimester of pregnancy, prolactin in the third trimester of pregnancy, estradiol in the first trimester of pregnancy, and testosterone levels in the first trimester of pregnancy; women aged from 36 to 41 years - estradiol in the third trimester of pregnancy (has the largest contribution to discrimination) and estradiol in the 16 weeks of postpartum period. In general, the totality of all variables has a low level of discrimination between healthy and sick at OAB women between the ages of 17 and 25 (Wilkes Lambda statistics = 0.679; F = 131.4; p <0.001) and ages 26-35 (Wilks Lambda statistics = 0.493; F = 224.9; p <0.001), while among women between the ages of 36 and 41 - the average level of discrimination (Wilkes Lambda statistics = 0.371; F = 207.4; p <0.001). Thus, with the aid of discriminant analysis, reliable models of the possibility of OAB occurrence, based on anthropo-somatotypological or hormonal indices in women of different age groups, are constructed. In all age groups, the greatest contribution to discrimination between healthy and sick with OAB pregnant women, in most cases, make parameters of the width of distal epiphyses of long limb bones or the level of estradiol. en
dc.language.iso en_US en
dc.publisher Biomedical and biosocial antropology en
dc.subject discriminatory analysis en
dc.subject pregnant women en
dc.subject overactive bladder syndrome en
dc.subject anthropometry en
dc.subject hormones en
dc.subject age en
dc.subject дискримінантний аналіз uk
dc.subject вагітні жінки uk
dc.subject синдром гіперактивного сечового міхура uk
dc.subject антропометрія uk
dc.subject гормони uk
dc.subject вік uk
dc.subject дискриминантный анализ ru
dc.subject беременные женщины ru
dc.subject синдром гиперактивного мочевого пузыря ru
dc.subject антропометрия ru
dc.subject гормоны ru
dc.subject возраст ru
dc.title Modeling the possibility of occurrence of overactive bladder in women of different ages, depending on anthropo-somatotypological indicators or hormonal background with the help of discriminant analysis en
dc.title.alternative Моделювання за допомогою дискримінантного аналізу можливості виникнення гіперактивного сечового міхура у жінок різного віку в залежності від антропо-соматотипологічних показників або гормонального фону uk
dc.title.alternative Моделирование с помощью дискриминантного анализа возможности возникновения гиперактивного мочевого пузыря у женщин разного возраста в зависимости от антропо-соматотипологических показателей или гормонального фона ru
dc.type Article en


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