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The course of bronchial asthma associated with metabolic syndrome in children with different phenotypes depending on vitamin D3 level

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dc.contributor.author Protsiuk, T. L. en
dc.contributor.author Herasymova, Ye. V. en
dc.contributor.author Protsiuk, L. O. en
dc.contributor.author Surkova, N. M. en
dc.date.accessioned 2018-11-07T10:28:18Z
dc.date.available 2018-11-07T10:28:18Z
dc.date.issued 2018
dc.identifier.citation The course of bronchial asthma associated with metabolic syndrome in children with different phenotypes depending on vitamin D3 level / T. L. Protsiuk, Ye. V. Herasymova, L. O. Protsiuk, N. M. Surkova // Pathologia. - 2018. - Vol. 15, № 1. - Р. 68-73. en
dc.identifier.issn 2306-8027
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/3185
dc.description.abstract To establish specific features of BA course in children with various phenotypes on the background of metabolic syndrome, depending on serum vitamin D3 level. 106 children with BA participated in the study. 42 patients had BA associated with metabolic syndrome (MS), and 64 had BA with no MS. By the phenotype 61 (57.5 %) of patients had allergen-induced (allergic) asthma and 45 (42.5 %) – virus-induced (non-allergic) BA. The severity of BA as well as the degree of its control in the patients with different phenotypes was found to be influenced by both the presence of MS and vitamin D3 level. Therefore, vitamin D deficiency can be one of the risk factors of BA and MS development, and can affect the severity of both BA and MS course. Vitamin D3 deficiency and the presence of MS greatly influence FEV1, FVLC, PEF values, decreasing the indices of external respiration in children and leading to more severe obstruction. en
dc.language.iso en_US en
dc.subject asthma en
dc.subject syndrome metabolic en
dc.subject children en
dc.subject vitamin D3 en
dc.title The course of bronchial asthma associated with metabolic syndrome in children with different phenotypes depending on vitamin D3 level en
dc.title.alternative Особливості перебігу бронхіальної астми на тлі метаболічного синдрому в дітей із різними фенотипами залежно від показників вітаміну D3 uk
dc.type Article en


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