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dc.contributor.author Konkov, D. G. en
dc.contributor.author Zaporozhan, V. M. en
dc.contributor.author Grinevich, V. N. en
dc.date.accessioned 2017-10-18T15:08:49Z
dc.date.available 2017-10-18T15:08:49Z
dc.date.issued 2014
dc.identifier.citation Konkov D. G. Abnormal spiral artery remodelling in the decidual segment during gestational endotheliopathy / D. G. Konkov, V. М. Zaporozhan, V. N. Grinevich // Proceedings of the 3rd European Conference on Biology and Medical Sciences / «East West» Association for Advanced Studies and Higher Education GmbH. – Vienna, 2014. - P. 76-81. en
dc.identifier.isbn 3-902986-75-1
dc.identifier.isbn 978-3-902986-75-7
dc.identifier.uri https://dspace.vnmu.edu.ua/123456789/1096
dc.description.abstract Objectives: In early human pregnancy placental trophoblasts migrate along uterine spiral arteries (SAs) and remodel these vessels into wide-bore conduits in a process essential for successful pregnancy. This work examined the consequences of the preclinical and manifest forms of gestational endotheliopathy (GE) on the adequacy conversion of the SAs and the main characteristics of the trophoblast migration. Study design: 58 specimens of the placental tissues were obtained at 6-9 weeks of physiological pregnancy and pregnancy with gestational endotheliopathy. There were investigated histometrical and morphometrical parameters that were reflected the processes of optimal transformation of SAs during the first trimester. Results: It was found that pregnancy with gestational endotheliopathy was accompanied by the significant decrease of the values of perimeter, cross-sectional area, and lumen in the SAs. In addition, we obtained reduction of intensity of the vascular invasion internally cytotrophoblast and depression of the interstitial trophoblast invasion in GE, also. Conclusion: Abnormal transformations of the SAs was more common in specimens of the placental tissues from women with GE. en
dc.language.iso en en
dc.publisher «East West» Association for Advanced Studies and Higher Education GmbH. Vienna en
dc.subject gestational endotheliopathy en
dc.subject spiral arteries en
dc.subject trophoblast migration en
dc.subject perinatal pathology en
dc.title Abnormal spiral artery remodelling in the decidual segments during gestational endotheliopathy en
dc.type Article en


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