Короткий опис (реферат):
Abstract.Background and aim of the work: Undoubtedly, studying the clinical features of wound infection is relevant in the modern world, especially in Ukraine due to war. The main goal was to prevent possible remote consequences of wound healing and we studied the impact of wound microbiota in this aspect. Research design and Methods: We conducted a microbiological study of wounds among 51 patients with limb injuries. The age characteristics of the groups did not differ from each other. Also, 30 patients were interviewed using VAS pain to conduct an association between pain severity and the wound microbiota composition. Statistical calculations were performed using a computer program MedCalc®Software. Results: We divided patients into two groups: 1 group with one isolated an opportunistic wound pathogen and group 2 in which two or more types of opportunistic wound pathogens were isolated. The number of microbial associations formed by gram-negative species of microorganisms was determined in 1.78 times more often than the colonization of wounds by gram-positive opportunistic microorganisms. The surveyed respondents were divided into subgroups 1.1 and 2.1. The average value of pain in subgroups 1.1 and 2.1 was 38.46 (SD ± 13.44) and 39.16 (SD ± 13.78) and did not differ statistically (p > 0.05). Conclusions: The predominance of gram-negative microorganisms as Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus spp., Pseudomonas aeruginosa was established. The sensation of pain did not depend on the number of colonizing species. The obtained data encourage fur-ther research into the role of microorganisms in the healing process. (www.actabiomedica.it)